Nr 565 advanced pharmacology fundamentals week 7 final exam
Health Care / Exam
NR565 Week 7 & Final Exam Study Outline Many questions are written to assess your clinical application of the material from the textbook, in real-world scenarios. Week 7 Readings: Chapter 34: Gastroesophageal reflux and peptic ulcer disease Know the following for each drug class (antacids, antidiarrheals, cytoprotectives, antiemetics, histamine 2 receptor antagonists, prokinetics, proton pump inhibitors and laxatives): Antiacids: neutralize acids in the gastrointestinal (GI) tract. Different combinations have differing acid neutralizing capacities. Sodium bicarbonate and calcium carbonate have the highest absolute neutrophil count (ANC) ALLUMINUM HYDROXIDE (Aluminum Carbonate (Basalgel) AE constipation TX: Hyperphosphatemia MAGNESIUM HYDROXIDE AE diarrhea ALLUMINUM/MAGNESIUM HYDROXIDE Highest ANC CALCIUM CARBONATE AE constipation TX (TUMS) calcium deficiency in chronic renal failure, post menopause, osteoporosis Drug interactions: many affect absorption of most drugs, separate antiacid administration with other drugs for at least 2 hrs. Pharmacodynamics: Antiacids neutralize gastric acid in the GI tract. Causing an increase PH in the stomach and duodenal bulb. Antacids contain various combinations of metallic cation. * different combinations have different acid neutralizing capacities. Metallic cation + basic ion, common metallic cation, aluminum, calcium, magnesium, bests anion, hydroxide, bicarbonate, carbonate. Clinical use: Hyperacidity: antacids used for relief of heart
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